性激素基础值的临床意义及实验室诊断（Clinical significance and laboratory diagnosis of sex hormone basal value）.docVIP

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性激素基础值的临床意义及实验室诊断（Clinical significance and laboratory diagnosis of sex hormone basal value）.doc

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性激素基础值的临床意义及实验室诊断（Clinical significance and laboratory diagnosis of sex hormone basal value）

性激素基础值的临床意义及实验室诊断（Clinical significance and laboratory diagnosis of sex hormone basal value） First, the gonad function test items and clinical significance Sex hormone is secreted by adrenal cortex or sexual organs, maintaining and regulating the body in normal life, a class of steroid hormones and physiological activities of reproductive function. In the different stages of individual growth, despite the different levels of sex hormones, or the ratio of androgen and estrogen is different, but according to the needs of the body in a dynamic balance, if the imbalance, or organ hormone secretion dysfunction, will induce a series of tissue, organ dysfunction or pathological change. The function of sex hormones and the level of plasma sex hormones in sex organs. The regulation of gonadotropin directly secreted by the pituitary gland is also influenced and regulated by GnRH released by the hypothalamus. Sex hormones including testosterone, dihydrotestosterone (T) (DHT), estradiol (E2), female three alcohol (E3), estrone (E1), progesterone (P), in addition, placental lactogen secretion of placental hormone (HPL), human chorionic gonadotropin (HCG) secreted by the adrenal gland and dehydrogenation dehydroepiandrosterone (DHEA), 17 alpha hydroxyprogesterone (17- alpha -OH) and androst-4-ene-3,17-dione in two (A2). Two. Clinical significance and laboratory diagnosis of sex hormone basal value: (1) precocious puberty, estrogen secretion of tumor and exogenous pseudoprecocity E2 increased significantly, while the simple early breast development of their estrogen level is not high or slightly high, the determination of FSH and LH is helpful to distinguish true or false sexual precocity. (2) sexual immaturity, because of ovarian dysfunction, cannot produce enough sex hormones, resulting in elevated levels of FSH and LH, and low levels of E2. (3) postmenopausal women in the differential E2 level is very low, about 50% were below the sensitivity conventional measurement methods, t