实验设计的基本原则（Basic principles of experimental design）.docVIP

实验设计的基本原则（Basic principles of experimental design） Basic principles of experimental design Basic principles of medical research Randomization principle A comparative principle The principle of blindness Repeatability principle Balanced distribution The purpose of setting up these principles is to ensure that the results of the study are not affected by known or unknown bias factors, and that the findings and conclusions are more authentic and reliable. Randomization principle 1. concepts and uses The research task is to set aside a certain number of objects from the overall research samples obtained, and overall. To make a sample representative of the population, the sampling error must be reduced. Concept: randomization refers to the fact that each individual in the population has equal opportunities to be taken as a sample or assigned to the experimental group and the control group to study. The purpose of random sampling and grouping is to avoid human subjectivity and to make the opportunity work to reflect the overall objective situation. The core of the randomization principle is equal opportunity. The actual meaning of randomization refers to randomization in the sampling, grouping and implementation of subjects. Concrete embodiment: The random sampling: every eligible subjects participated in the experiment of the same opportunity, namely in each individual has the same opportunity to be drawn in to the sample. The random grouping: each subject divided into treatment group and control group of the same opportunity, to ensure that each treatment group subjects as balanced as possible, in order to improve the comparability between groups. The experiment of random order: each subject has the same chance of receiving treatment, to eliminate the deviation of experimental order imbalance caused by. Random is not random and casual. Animal grouping: mice grouping Patients group: surgical patients with acute abdomen were treated with conservative treatment and surgica