炎症性肠病临床表型与免疫标记物的相关性.pdfVIP

冒题痘堂垫!!生笠!!鲞筮!塑 ·371· 炎症性肠病临床表型与免疫标记物的相关性+ 孙瑾1 于成功∽。 南京大学医学院附属鼓楼医院消化内科2 南京医科大学鼓楼临床医学院1(210008) 摘要炎症性肠病(IBD)是一种病因不明的慢性肠道疾病，包括克罗恩病(CD)和溃疡性结肠炎(UC)。研究 显示，多种免疫标记物与IBD的临床表型密切相关，正确认识这些标记物将有助于IBD的诊断分型、判断疾病活动 程度以及预测疾病预后等。本文就免疫标记物与IBD临床表型的关系作一综述。 关键词炎症性肠病；Crohn病；结肠炎，溃疡性；临床表型；生物学标记 Diseaseand Markers betweenClinical of Bowel SUN以凡。． Inflammatory Immunological Relationship Phenotypes YU 。DrumTowerainwalMedical Medwal Chenggong坩． School，Nanjing DrumTower Medwal ofGastroenterology，TheAffiliated Hosp打alofNanjingUniversity School，Nanjing to：YU CorrespondenceChenggong．Email：chenggong．yu@gmail．COB intestinaldiseaseswithunknown Abstract bowel a ofchronic Inflammatorydisease(IBD)is etiology， group markersbe Crohn’s ulcerative haveindicatedthat could including disease(CD)andcolitis(UC)．Studies immunological withclinical ofIBD．Thecorrect ofthesebiomarkerswillcontributetothe associated understanding closely phenotypes and of theevaluationofdisease andtothe of article diagnosissubgroupingIBD，to activity predictionprognosis．This clinical ofIBD． reviewedthe between markersand relationshipimmunological phenotypes words Bowel Crohn Clinical