损伤的修复repair.PDFVIP

损伤的修复 repair What is tissue repair ? 修复：损伤造成机体部分细胞和组织丧失后，机体对所形成缺损 进行修补恢复的过程 Tissue repair is the response of organisms to overcome the damage caused by toxic insults, inflammation and trauma. Regeneration Normal Scar formation Review of Repair Responses Two types： 再生 (regeneration)：邻近同种细胞通过分裂增殖以完成修复的现象。 如完全恢复了原组织的结构与功能，则为完全再生 Some tissues are able to replace the damaged cells and tissues in its entirety (regeneration) replacement of functional, differentiated cells 纤维性修复(fibrous repair) ：通过肉芽组织增生，填补组织缺损，并 逐渐转化为瘢痕组织的现象 If the tissue injury is too severe and regeneration is not possible, repair occurs by laying down fibrous tissue (healing) that results in scar formation. Injured tissue can usually function despite the presence of scars. production of a fibrous scar 第一节 再 生 （regeneration） 再生是指组织、细胞损伤后，缺损周围健康细胞 的分裂增殖。再生可分为生理性再生和病理性再生。 Regeneration refers to growth of cells and tissues to replace lost structures, such as the growth of an amputated limb in amphibians Regeneration can be defined as the natural ability of living organisms to replace worn out parts, repair or renew damaged or lost parts of the body, or to reconstitute the whole body from a small fragment during the post embryonic life of an organism. Regeneration is thus also a developmental process that involves growth, morphogenesis and differentiation. 生理性再生(physiologic~) ：生理过程中，细胞、组 织老化、消耗，由新生的同种细胞不断补充，保持 原有 结构和功能 There is a constant loss of many kinds of calls due to wear and tear caused by day-to-day activities. The replacement of these cells is known as physiological regeneration Example: Replacement of R.B.Cs 病理性再生(pathologic~)：病理状态下细胞、 组织缺损后发生的再生。可为完全再生，也可不 完全再生 Reparative Regeneration This is the replac