注射用尤瑞克林治疗急性后循环梗死的疗效分析[J].pdfVIP

中国卒中杂志 2010年4月 第5卷 第4期 299 ・论著 ・ 注射用尤瑞克林治疗急性后循环梗死的 疗效分析 李轶，龚浠平，陈启东，曲辉，董可辉 【摘要】 作者单位 目的 观察静脉注射人尿激肽原酶（尤瑞克林）对急性后循环梗死患者的疗效。 100050 北京市 方法 选择后循环梗死的急性期患者68例，随机分为尤瑞克林治疗组（人尿激肽原酶治疗14d）和 首都医科大学附属北京 天坛医院神经内科 对照组，观察两组患者在治疗前及治疗后14d、90d的神经功能缺损评分。 通信作者 结果 尤瑞克林治疗组和对照组患者在治疗14d、90d后神经功能缺损程度均有不同程度改善，而使 龚浠平 用人尿激肽原酶组患者在治疗后的神经功能恢复情况较对照组有明显改善。 xiping_gong@. 结论 人尿激肽原酶可能有助于改善后循环梗死患者的临床预后。 cn 【关键词】 尤瑞克林；脑梗死 Effect of Urinary Kallidinogenase Injection in Patients with Posterior Ischemic Stroke LI Yi, GONG Xi-Ping, CHEN Qi-Dong, et al. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China 【 】 Abstract Objective To observe the effect of Urinary Kallidinogenase in patients with posterior ischemic stroke. Methods Sixty-eight patients with posterior circulation stroke were included in this trial and all patients were randomly divided into two groups. Patients (n=34) in the treatment group were treated with Urinary Kallidinogenase injection and basic therapy for 14 days after inclusion, while the control group was treated with physiological saline and basic therapy. National institutes of health stroke scale NIHSS and Barthel index was evaluated pre and 14d, 90d after inclu