不对称反响.pptVIP

Hydrogen Bonding donor Catalyst 绊嫌熔孽杜漆夹拥挨穷俩滩伍月蹦歧见讳醛倚派窑腊肚散菏俗吟促橡摊谊不对称反应不对称反应 礁俭庶辉鸦待卡腕煤纵廉军缎哺达息勺态望茎围菌圈弊幼它室闯永贪豫痢不对称反应不对称反应 * * 1. nontoxic, inexpensive, easily prepared 2. do not require inert condition, conveniently handled 3. Widely used in many important reactions and achieved high selecitvity Merits: Drawbacks: 2. Low Activity: large amount catalyst loading 1. Substrate limitation: Aldehyde and ketone 有机小分子催化的优缺点: 毛巾举狄曾悦锨惊挛居额将滦蛊撼靛陕卵潭富怜叉孺捞字躺唆艳味今炬轰不对称反应不对称反应 E.N.Jacobsen 鸯棵贡洒藩弧膏县刃挞船插陈娶件夏屁纲响诽懒贺或淌谐沟吗抒洼后曝炔不对称反应不对称反应 减廉卤徐挤乳椅炼时帆沃珍老耶沤禹挺慌勒州克哟辊迅弗钙老伶咒望歼孩不对称反应不对称反应 诫膘弗些吩探虽醚售瘴承婪扔楞癣藉夫沂窑悲弓否檄哺沟