补佳乐联合黄体酮序贯与克龄蒙治疗幼稚型子宫临床疗效比较.docVIP

补佳乐联合黄体酮序贯与克龄蒙治疗幼稚型子宫临床疗效分析 朱静1，刘建梅，程湘* 重庆新桥医院妇产科 400037 [摘要] 目的 探讨补佳乐联合黄体酮序贯与克龄蒙治疗幼稚子宫的疗效。方法：选择50例幼稚子宫的患者，随机分二组，A组（25例）为补佳乐联合黄体酮序贯治疗组，B组（25例）为克龄蒙治疗组，所有入选患者在首次治疗的3、6个月内随访阴道撤退性出血的情况、子宫大小、血雌二醇与孕酮、临床疗效等。结果 A、B两组在首次治疗的3、6个月内随访，阴道撤退性出血平均时间、血孕酮值、子宫大小、临床疗效，A组优于B组，有显著性差异（P 0.05）。但是，治疗后3、6月，两组血雌二醇值无明显差异（P 0.05）。结论 补佳乐联合黄体酮序贯治疗效果优于克龄蒙治疗幼稚子宫。 [关键词] 幼稚子宫；补佳乐；黄体酮；克龄蒙 [中国分类号] [收稿日期] [修回日期] Clinical Analysis Of Progynova Combined With Progesterone and Climen On Infantile Uterus Jing Zhu, Jianmei Liu, Guilan Lin, Xiang Cheng (Department of Gynaecology and obstetrics, Xinqiao Hospital of Tmmu, ChongQing 400037, China) Abstract：Objective To study the effects of progynova combined with progesterone on infantile uterus. Methods Totally 50 patients with infantile uterus diagnosed by ultrasonography were randomized into 2 groups:group A (n=25) were treated with progynova combined with progesterone on infantile uterus, group B (n=25) were treated with Climen. All the patients were rechecked by ultrasonography and blood examination and so on method within 3 and 6 month after treatment .Results The follow-up went within 3 and 6 month after the first treatment. Time for Vaginal withdrawal bleeding, progesterone, measurement of uterus and clinical effective rates group A is better than group B. There were statistical differences between groups(P0.05),however, there weren’t statistical differences between groups on estradiol（P 0.05）. Conclusion Progynova combined with progesterone in the treatment of infantile uterus is more effective than Climen Keywords：infantile uterus, progynova, progesterone, Climen 前言： 幼稚型子宫是由副中肾管会合形成子宫后因某种原因短时间内停止发育引起的，是女性不能正常受孕的重要病因之一[1]。以往临床上使用己烯雌酚和醋酸甲羟孕酮片序贯治疗，但效果不理想[2]。本研究分别应用补佳乐联合黄体酮序贯和克龄蒙治疗幼稚子宫，取得了不同的效果，现报告分析如下： 临床资料 一般资料 1，第一作者，朱静，单位：重庆市新桥医院妇产科，邮箱：yeer198525@yahoo.cn *，通讯作者，程湘，单位：重庆市新桥医院妇产科，邮箱： 本文研究对象为2010年01月--2011年12月来我院门诊就诊的50名幼稚型子宫患者。入选标准：年龄13--16岁，腹部超声显示子宫长、宽、及厚度之和110mm，宫体与宫颈之比为 1∶1 或 2∶3[3]。根据治疗方案，我们把上述患者分为补佳乐与黄体酮序贯治疗组（A组）和克龄蒙治疗组（B组）。 1.2 治疗方法