MR医学影像文献Liao-2016-Tissue-engineered conduit promotes s.pdfVIP

Magnetic Resonance Imaging 34 (2016) 515–523 Contents lists available at ScienceDirect Magnetic Resonance Imaging journal homepage: Original contribution Tissue-engineered conduit promotes sciatic nerve regeneration following radiation-induced injury as monitored by magnetic resonance imaging☆ Chengde Liao a,⁎, Rui Zheng a, Changzheng Wei b, Jun Yan a, Yingying Ding a, Guangshun Wang a, Zhuolin Li a, Zhiping Zhang a a Department of Radiology, The Third Affi liated Hospital of Kunming Medical University, Yunnan Tumor Hospital, No. 519 Kunzhou Road, Kunming 650118, Yunnan, China b Shanghai Qisheng Biological Preparation Co, LTD, No.1008, Wucao Road, Shanghai, 201106, China a r t i c l e i n f o a b s t r a c t Article history: Purpose: To observe the longitudinal changes in peripheral nerve repaired with chitosan conduits in a rat Received 13 July 2015 model of radiation-induced neuropathy. Revised 3 December 2015 Materials and methods: Four months after 40 Gy radiation to the right lower limbs, forty-two rats were Accepted 7 December 2015 divided randomly into three groups. Chitosan conduits were implanted with (group A, n=12) or without (group B, n=12) mesenchymal stem cells (MSCs), and untreated controls (group C, n=12). Following Keywords: sciatic nerve MR imaging (including T2WI and Gd-DTPA enhanced T1WI), functional evaluation and Peripheral nerve injury