MR医学影像文献Sun-2016-Diffusion-Weighted Imaging-guided MR.pdfVIP

Eur Radiol (2016) 26:1565– 1574 DOI 10.1007/s00330-015-4000-0 BREAST Diffusion-Weighted Imaging-guided MR Spectroscopy in Breast Lesions using Readout-Segmented Echo-Planar Imaging Kun Sun 1 Weimin Chai 1 Caixia Fu3 Ying Zhan 1 Kunwei Shen2 Xianfu Luo 1 1 Fuhua Yan Received: 17 March 2015 /Revised: 13 August 2015 /Accepted: 2 September 2015 /Published online: 19 September 2015 # European Society of Radiology 2015 Abstract curves were 0.93 and 0.90, respectively. The mean tCho SNR Purpose To investigate the feasibility and effectiveness of and concentration negatively correlated with apparent diffu- diffusion-weighted imaging (DWI)-guided magnetic reso- sion coefficients calculated from RS-EPI, with correlation co- nance spectroscopy (MRS) using readout-segmented echo- efficients of −0.54 and −0.48, respectively. planar imaging (RS-EPI) to characterise breast lesions. Conclusion DWI-guided MRS using RS-EPI is feasible and Materials and methods A total of 258 patients with 258 sus- accurate for characterising breast lesions. picious breast lesions larger than 1 cm in diameter were Key Points examined using DWI-guided, single-voxel MRS with • The mean tCho SNR and concentration negatively correlat- RS-EPI. The mean total choline-containing compound ed with ADCs. (tCho) signal-to-noise ratio (SNR) and concentration • DWI-guided MRS using RS-EPI is feasible. were used for the interpretation of MRS data. T-tests, • DWI-guided MRS using RS-EPI accurately characterises χ2-tests, receiver operating characteristic (ROC) curve breast lesions. analyses and Pearson correlations were conducted for statistical analysis. Results Histologically, 183 lesi