肿瘤问题resources.ppt

CANCER: Stroma: ANGIOGENESIS ANGIOGENESIS / CANCER INVASION ANGIOGENESIS / CANCER INVASION ANGIOGENESIS / CANCER INVASION VEGF Rs ANGIOGENESIS / CANCER INVASION ANGIOGENESIS / CANCER INVASION ANGIOGENESIS / CANCER INVASION Enigmas APOPTOSIS Mitochondrion / Cytoplasm Mitochondria-death Signal Integrators Enigmas in Apoptosis HOT SPOTS OF SIGNALING Human RPTK Human Cytoplasmic PTK PI(3)K / Akt mTOR / p7056k (rapamycin target) Akt ( PKB ) Substrate of Akt-1 Substrate of Akt: 13: RXRXXS/T motif  (this motif:also for MAPKAPK-1