异丙酚复合氟比洛芬酯在无痛人流术中临床应用探究.docVIP

异丙酚复合氟比洛芬酯在无痛人流术中临床应用探究 　　[摘要] 目的 探讨异丙酚复合氟比洛芬酯在无痛人流术中的临床疗效及安全性。 方法 将100例自愿选择无痛人工流产的患者随机分为两组各50例，Ⅰ组为异丙酚组，Ⅱ组为异丙酚复合氟比洛芬酯组。观察两组患者异丙酚的用量、镇痛效果、平均动脉压、心率、经皮血氧饱和度的变化及术后宫缩痛VAS评分差（VAS5分）的情况。 结果 Ⅰ组异丙酚总用药量明显多于Ⅱ组，有明显统计学意义（P5分）的患者数明显多于Ⅱ组。 结论 异丙酚复合氟比洛芬酯在无痛人流术中效果明显优于单用异丙酚，联合用药提高了手术的安全性，减少用药剂量，减轻患者的痛苦，可以在临床上进一步推广应用。 [关键词] 氟比洛芬酯；无痛人流；临床研究 [中图分类号] R614 [文献标识码] B [文章编号] 1673-9701（2013）34-0111-02 Clinical application of propofol combined with flurbiprofen in painless abortion LAN Lixia1 PING Yongmei1 YAN Jing2 WANG Xiaofen1 1.Anesthesia Department， Lishui City MCH in Zhejiang Province， Lishui 323000， China；2.Anesthesia Department， Lishui City People’s Hospital in Zhejiang Province， Lishui 323500， China [Abstract] Objective To investigate the clinical efficacy and safety of propofol combined with flurbiprofen in painless abortion. Methods The 100 cases of voluntary induced abortion were randomly divided into two groups，50 cases in each group，GroupⅠwas propofol group， group Ⅱ was propofol plus flurbiprofen group. Observed two groups of patients propofol dosage， analgesic effect，mean arterial pressure，heart rate，transcutaneous oxygen saturation changes and postoperative uterine pain VAS score difference （VAS5points） situation. Results GroupⅠwas significantly more than group Ⅱin the total dosage of propofol，there were statistically significant （P5 minutes） significantly more than in group Ⅱ. Conclusion Propofol combined with flurbiprofen better than single-use propofol in painless surgery，Combination therapy improves the safety of surgery，reduce the dosage to alleviate the suffering of patients can be further in clinical application. [Key words] Flurbiprofen； Painless abortion； Clinical research 目前临床上行无痛人工流产手术时主要选用异丙酚等药物进行静脉麻醉，但是因为其镇痛效果差，常常需要增大药物剂量或者是联合一些镇痛药（芬太尼、氯胺酮等）才能达到无痛效果，保证手术顺利进行下去[1]。增大剂量会影响患者的心跳和呼吸，出现呼吸系统和循环系统的不良反应。因此我们收集了100例在我院门诊行无痛人工流产的患者，对比了单用异丙酚与异丙酚复合氟比洛芬酯无痛人流术及其术后镇痛的效果及安全性。以评价氟比洛芬酯在无痛人工流产术中的价值。 1 对象与方法 1.1 对象 100例患者均来源于我院妇科门诊2013年5～7月收治的ASAⅠ～Ⅱ级、自