热切除的治疗方式radiofrequencyRF-第三军医大学学报.DOCVIP

文章编号：200812022 子宫肌瘤超声消融与MRI信号特征关系的研究 朱 丽1，陈文直1，陈锦云1，温海燕2，邓勇斌3，张 蓉3，王智彪1 （ 重庆医科大学:1生物医学工程系、重庆市生物医学工程学重点实验室、重庆市超声医学工程重点实验室—省部共建国家重点实验室培育基地，3超声医疗国家工程研究中心;2重庆市急救医疗中心，重庆 400016） 提要: 目的 探讨超声消融子宫肌瘤后磁共振信号变化的特征。资料与方法 65例患者共80个肌瘤在超声消融前1周及消融后4～8周行MRI检查，比较消融区消融前后T1加权/T2加权信号变化。结果 增强扫描：治疗前灌注率98.8%（79/80）,治疗后灌注率8.8%（7/80）。T1加权：消融前高、等、低信号分别占1.3%、91.2%和7.5%；消融后依次占83.8%、16.2%、0；消融后高信号肌瘤消融率100%（67/67），等信号肌瘤消融率35.3%(6/13)，消融率差异显著（P0.05）;信号变化（均变成高信号）66个肌瘤，消融率100%（66/66），信号不变14个肌瘤，消融率50%（7/14），消融率差异显著（P0.05）。T1加权高信号区域体积与消融体积直线相关（r=0.93，P0.05）。T2加权信号变化与消融没有明显相关性（P0.05）。结论 超声消融子宫肌瘤后早期MRI的T1加权高信号，可成为判断肌瘤出现凝固性坏死的标准之一。 关键词:子宫肌瘤；超声消融；磁共振信号（T1加权/T2加权） 中图分类号: R737.33 Preliminary Study on relationship between Ultrasound Ablation For Uterine Fibroids and signal of MR Imaging ZHU Li1, CHEN Wen-zhi1, CHEN Jin-yun1, WEN Hai-yan,DENG Yong-bin,ZHANG Rong,WANG Zhi-biao (1Department of Biomedical Engineering, 3Institute of Ultrasonic Engineering in Medicine, Chongqing Medical University, 2Center of emergency treatment, Chongqing 400016 China) Abstract: Objective To explore the characteristic of signal of MR imaging after ultrasound ablation for uterine fibroids. Materials and Methods 65 patients with 80 uterine fibroids were gievn MRI 1 week before and 4～8 weeks after the therapy. Detecting T1-weighted/T2-weighted and comparing the changes of the signal. Results The filling rate was 98.8%（79/80） before therapy, but 8.8%（7/80） after therapy on contrast-enhanced scanning. Befoe therapy on T1-weighted: high-signal 1.2%、intermediate-signal 91.3%、low-signal 7.5%；after therapy 83.8%、35.3%、 0 in turn; high-signal fibroids 100% (67/67) showed necrosis; intermediate-signal fibroids 35.3% (6/13) showed necrosis（P0.05); signal of 66 fibroids increased to high-signal, and 100% (67/67) showed necrosis. signal of 14 fibroids no changed, and 50% (7/14) show necrosis（P0.05); relationship of volume between high-signal area on T1-weighted and necrosis area was liner (r=0.93，P0.05). there was not obvious