脂肪间充质干细胞与自体髓核细胞共培养中相互作用分子机制初步分析-骨外科学专业毕业论文.pdfVIP

华 中 科 技 大 学 硕 士 学 位 论 文 and collagen II among two groups (P0.01). Immunohistochemical analysis showed that AMSCs started to express collagen II, the results of RT-PCR demonstrated that the gene expression of HIF-alpha, Sox-9, aggrecan and collagen type II, which were chondrocyte specific, were upregulated. There was significant difference in gene expression (P0.01). Conclusions The results showed a possible mechanism of interaction between AMSCs and NP cells mediated by secreted factors: ①NP cells promoted AMSCs differentiat