微胶囊制备新方法———乳滴模板法.PDFVIP

第 20 卷 第 78 期 化 　学 　进 　展 Vol. 20 No. 78 2008 年 8 月 PROGRESS IN CHEMISTRY 　Aug. , 2008 微胶囊制备新方法 ———乳滴模板法 刘红霞 　王朝阳 　高权星 　童 　真 (华南理工大学 材料科学研究所 　广州 510640) 摘 　要 　本文介绍一种新颖 、灵活的微胶囊制备方法 ———乳滴模板法 。胶体粒子在乳滴表面 自组装形 ( ) 成有序的球面胶体壳 ,交联固定乳滴表面的胶体粒子制备新型的“胶体体 colloidosome ”微胶囊 , 即以胶体粒 子为壳的微胶囊 。乳滴模板法制备微胶囊的优点是方法简单 ,胶囊的尺寸 、渗透性 、机械强度容易调控 。这 种新型的微胶囊在功能食品、药物载体 、生物医药 ,尤其是细胞移植等领域具有潜在的应用前景 。 关键词 　乳滴模板法 　胶体粒子 　微胶囊 　自组装 ( ) 中图分类号 : O647. 3 ; TB383 　文献标识码 : A 　文章编号 : 1005281X 2008 078104406 Preparation of Novel Microcapsules by Emulsion Droplet Template Method Liu Hongxia 　Wang Chaoyang 　Gao Quanxing 　Tong Zhen (Research Institute of Materials Science , South China University of Technology , Guangzhou 510640 , China) Abstract 　The present article focuses on a facile and versatile technique of emulsion droplet template method , developed for preparing novel microcapsules. Colloid particles adsorb on the surface of the emulsion droplets and self assemble into an ordering spherical solid shell. Crosslinking and fixing the shell , the novel capsule “colloidosome ”, which is composed of a closepacked shell of colloid particles , can be fabricated. The strategy outlined readily affords the facility of fabrication and precise control over the size , permeability , mechanical strength of the capsules. Consequently these capsules have potential applications in functional foods , drug delivery , biomedicine , especially cell transplant.