列当不同提取物降糖作用研究.PDF

第8 卷 第8 期 食品安全质量检测学报 Vol. 8 No. 8 2017 年8 月 Journal of Food Safety and Quality Aug. , 2017 列当不同提取物降糖作用研究 * 胡安古丽·努尔别克, 赛福丁·阿不拉 , 那尔胡兰·再肯, 阿依姑丽·买买提明 (新疆农业大学动物医学学院, 乌鲁木齐 830052) 摘 要: 目的 研究列当不同提取物的降糖作用。方法 本试验提取列当多糖、醇提物及水提物, 应用四氧 嘧啶建立小鼠糖尿病模型, 并对列当提取物的降血糖作用进行综合评价。结果 多糖和醇提物的低剂量、水 提物中剂量均可显著降低小鼠的血糖值(P0.05) 。其中醇提物低剂量组效果明显, 对糖尿病具有一定的预防及 治疗作用。多糖低剂量、醇提物和水提物的高剂量对体重的作用比较明显, 其中水多糖低剂量组对糖尿病小 鼠的体重有明显的提高。多糖3 个剂量和醇提物中剂量、水提物高剂量组显著降低小鼠血脂(P ＜0.05) 。结论 列当不同提取物多糖、水提物、醇提物具有明显的降血糖作用。 关键词: 列当; 降血糖; 提取物 Hypoglycemic effects of different extracts of Orobanche coerulescens Steph HUANGULI-Nuerbieke, SAIFUDING-Abula, NAERHULAN-Zaiken, AYIGULI-Maimaitiming (College of Veterinary Medicine, Xinjiang Agricultural University , Urumqi 830052, China) ABSTRACT: Objective To study the hypoglycemic effects of different extracts of Orobanche coerulescens Steph. Methods Orobanche coerulescens polysaccharide, ethanol extract and water extract were prepared, diabetic mice model was established by alloxan, and the hypoglycemic effects of Orobanche coerulescens extracts were comprehensively evaluated. Results The low dose of polysaccharide, low dose of alcohol extract and medium dose of water extract could significantly reduce the blood glucose in mice (P0.05). Among them, the low dose of alcohol extract group had obvious effect, and had certain preventive and therapeutic effects on diabetes. The low dose of polysaccharide,