西洋参卷片生产工艺研究.pdfVIP

目 录 摘要I-II 1 前言1 2 材料与仪器2 2.1 设备2 2.2 原料和试剂2 3 实验方法与结果3 3.1 试验研究（小试）3 3.2 中试放大8 3.3 西洋参卷片生产工艺完整验证8 4 讨论27 4.1 质量西洋参卷片标准27 4.2 西洋参质量差异对粗选收率情况的影响27 4.3 润药分析27 4.4 切制分析28 4.5 阴干分析28 5 结论28 参考文献30 综述32 致 谢40 西洋参卷片生产工艺研究 摘要：目的 为保证西洋参卷片生产质量和生产效率的进一步提升，对西洋参卷片生产工艺 进行再次参数细化研究，确定更加合理的相关工艺参数，并选择3批西洋参原料 对其全程工艺流程进行验证，确保西洋参卷片生产质量更加稳定且更有利于质 量控制。方法 整个过程包括试验研究（小试）、中试放大、验证生产3个阶段。其中试验研究，有 针对性地对西洋参的闷润、切制和阴干3方面的工艺参数进行了详细研究；中试 放大时，进行3批相当于最小生产量物料进行试制；验证生产阶段，进行了连续3 批西洋参物料生产，选择日常生产量为验证生产量，严格按GMP要求操作管理， 工艺按审批验证方案开展执行。结果 最佳生产工艺参数为：润药：较硬西洋参润药时间为10~10.5小时，期间淋水2次， 较软西洋参润药时间为3~3.5小时，期间淋水1次；切制：西洋参切片机机器切制厚 度最佳参数为0.5mm~0.8mm ；阴干：在阴干厚度为1~1.5cm下阴干3- 4小时左右；细选：过5 目筛进行大小分档，筛选出一等西洋参卷片。结论：经过再 次研究的重要参数下所进行的西洋参卷片生产工艺能生产出优等质量且易进行 质量控制的西洋参卷片，给西洋参卷片生产带来重要益处。 关键词：西洋参；工艺参数；收率；物料平衡率 Research of the production process of Panax quinquefolium L Abstract: Objective in order to ensure the production quality and promote the production efficiency of Panax quinquefolium L , Research and verification of the production process of Panax quinquefolium L was studied again after several improvements. As a result, more reasonable related process parameters have been made. Besides, 3 batches of American ginseng raw material were selected to confirm along the whole process. The study was to make sure the production quality of American ginseng more stable and easily controlled. Methods the whole process consists of 3 stages (first test, second test, verification of production). In the first test, the parameters of Panax quinquefolium moistening, cut and dried in the shade were studied in detail; In second test, the 3 batches of material which were equivalent to the minimum amount of production were tested; In the verification of production, the 3 batches of American ginseng were produced one by one and the daily prod