论文常用句型摘抄.docx

sci论文常用句型摘抄Taken together, our data provide new mechanistic insights into possible endogenous signaling metastatic signaling pathways involved in maintaining proliferation and migration of breast cancer cells.We sought to determine whether seliciclib (CYC202, R-roscovitine) could increase the antitumor effects of doxorubicin, with no increase in toxicity, in an MCF7 breast cancer xenograft model.MIB1 (ki67) immunohistochemistry demonstrated reduced proliferation with treatment.(用于ki67方面)Survivin embodies these properties, andMoreover, in pre-clinical bladder tumor models, inhibition of Survivin expression and/or function has been shown to impede tumor cell proliferation, and markedly induce spontaneous or chemotherapy induced apoptosisThe efficacy of mainstay cancer therapies, cytotoxics and radiation, has reached a plateau in the treatment of many cancers, and there is an urgent sense that improvements must now come from fresh approaches.Median age was 62 years with a range of 40-74 years.splice variants might function in effect as dominant negatives so that their expression might concurrent with survivin.There is a hypothesis thatThe absence of in vivo data on this point has now been remedied with a paper in this issue of the JCI by Altieri and colleagues.Thus, this raises an interesting question whether... raising the possibility that most, if not all, tumors express...The levels of p21 and p27 increased after treatment with doxorubicin or seliciclib alone or in combination, compared to untreated controls.In contrast, it is abundantly expressed in a wide variety of malignant tissues.On the contrary,... By contrast, a good title will attract the relevant researchers and increase the number of citations you receiveWe have found that the human breast cancer cells MCF-7/Adr overexpress not only P-gp but also XIAP and Survivin, and showed high resistance to chemotherapeutic drugs doxorubicin, docetaxel and vincristine, in contrast to their parental cells KB and MCF-7.