甲状腺功能亢进论文：妊娠合并甲状腺功能亢进对妊娠结局的影响.docVIP

甲状腺功能亢进论文：妊娠合并甲状腺功能亢进对妊娠结局的影响 【中文摘要】通过测定FT3、FT4、TSH、β2-mG值，探讨甲状腺功能亢进对妊娠结局的影响及其之间的关系。方法：回顾性分析山西医科大学附属第一医院、大同第一人民医院2009年10月——2011年10月期间就诊产科门诊与住院患者妊娠伴甲亢症患者63例，发病率为5.2，按照病情控制情况分为未控组（28例）和控制组（35例），随机选取同期正常妊娠30例为对照组，通过测量比较各组血清中的甲功3项和β2-mG值，探讨甲状腺功能亢进对妊娠结局的影响及其之间的关系。结果：1.三组血清TSH、FT3、FT4、β2-mG差别均有统计学意义，其中控制组血清TSH、FT3、FT4、β2-mG与未控组比较差别有统计学意义，且控制组血清FT3、FT4、β2-mG较未控组低。未控组血清TSH、FT3、FT4、β2-mG与对照组比较差别有统计学意义，未控组血清FT3、FT4、β2-mG高于对照组，血清TSH低于对照组。2、妊娠结局：未控组引产、早产、流产高于控制组（P 0.05）。3、妊娠并发症：未控组妊娠甲状腺危象、甲亢性心脏病高于控制组（P 0.05）。结论：妊娠合并甲状腺功能亢进的患者将甲状腺激素控制在理想范围，有利于减少孕妇不良妊娠结局及并发症的发生，孕妇的甲状腺功能与妊娠结局密切相关。 【英文摘要】: Determination of FT3and FT4, TSH,β2-m values, to explore the impact onpregnancy outcome and the relationship between hyperthyroidism.Methods: 63 cases of pregnancy with hyperthyroidism in the First Affiliated Hospital ofShanxi Medical University and Datong People抯 Hospital from Oct.2009 to Oct.2011 wereretrospectively analyzed. According to the control of hyperthyroidism, patients were dividedinto two groups : the disease-uncontrolled group（28 cases） and the disease-controlled group（35cases）. At the same time randomly selected normal pregnancy hospitalized in the same period，30 cases was as contrast group for comparsion. To explore the influence of pregnancy outcomefor hyperthyroidism and their relationship by measuring the comparison group in the serum ofa work five,β2-mG.Results: 1. The difference of TSH, FT3, FT4andβ2-mG levels amongdisease-controlled group, disease-uncontrolled group and contrast group were statisticallysignificant （P0.05）. The difference of clinical parameters among disease-controlled group anddisease-uncontrolled group statistically significant （P0.05）. The volume of FT3FT4andβ2-mG were higher （P0.05） in disease-controlled group than in disease-uncontrolled group.The difference of clinical parameters among disease-uncontrolled group and contrast groupstatistically significant （P0.05）. The volume of FT3FT4andβ2-m were higher （P0.05） indisease-uncontrolled group than in cont