基于组合学习算法的肺栓塞诊断模型-中国数字医学.PDFVIP

数字医学研究与应用 Research and Application of Digital Medicine 基于组合学习算法的肺栓塞诊断模型 ① ① ① 王星 王人福 王聪 摘 要 CT血管造影在肺栓塞临床诊断中有着广泛的应用，然而血管造影大都包含上百张肺部切片，人工筛选这些切片效率 低下出错率较高。尝试通过组合学习算法建立自动识别模型来有效提高识别能力，识别模型由三部分构成：数据的不平衡处 理，变量选择方法和组合学习模型。通过比较不同不平衡数据处理策略和变量选择方法的基础上，选择Adaboost方法进行分 类算法的学习，临床数据的结果表明该方法能较好地辅助实际诊断。 关键词 Adaboost SVM-SCAD 不平衡数据 Doi:10.3969/j.issn.1673-7571.2013.06.023 Pulmonary Embolism Diagnosis and Treatment Model Based on Combined Learning Algorithm / WANG Xing, WANG Ren-fu, WANG Cong//China Digital Medicine.-2013 8(6): 78 to 81 Abstract Computed Tomography Angiography (CTA) has become an accurate diagnostic tool for Pulmonary Emboli (PE). However, each CTA study consists of hundreds of images, each representing one slice of the lung. Manual reading of these slices is an inefficiency job with high misclassification rate. This paper is aimed to build models which can automatically identify the disease through a combination of learning algorithms. The proposed diagnostic model consists of three parts: the imbalance data processing, variable selection procedure and Boosting algorithm model. After comparing the result of different unbalance data processing strategies and different variable selection methods, the Bootstrap Adaboost learning model is chosen to conduct our classification task. Finally, results in clinical data shows that our model performed well. Keywords Adaboost, SVM-SCAD, imbalanced data Fund project Project Results of Scientific Research Foundation of Renmin University of China (funded by Special Funding for Basic Scientific Research Expenses of Central Universities) (No. 2013030273); Funded by Research Project of Tracking and Evaluation