血脂分析测试的国家指南.pptVIP

National Guidelines on Lipid Profile Testing  Preface Blood lipid analysis has a substantial importance towards the prevention and management of atherosclerosis and coronary heart disease (CHD). It is also being widely applied to the studies of many other related clinical conditions, such as diabetes mellitus, kidney diseases, and metabolic disorders in postmenopausal women. Recently, the Lipid Expert Panel of the Chinese Society of Laboratory Medicine (CSLM) of the Chinese Medical Association (CMA) has come up with the practical guidelines and recommendations on lipid profile testing. lipid profile testing: total cholesterol (TC) triglycerides (TG) high density lipoprotein–cholesterol (HDL-C) low density lipoprotein-cholesterol (LDL-C) apolipoprotein A1 (ApoA1) apolipoprotein B (ApoB) lipoprotein(a) [Lp(a)] The Guidelines include the content as follows, Preface Preanalytical factors affecting lipid test results Methods of lipid analysis Reagent selection criteria and practical guidelines Clinical significance of cutoff values in the interpretation of lipid profile results Preanalytical Factors Affecting Lipid Test Results A subject’s lipid profile should be measured when the individual is in a steady metabolic state. Subjects should maintain their usual diet and weight for at least 2 weeks prior to the measurement of their lipids or lipoproteins. Subjects should not perform vigorous physical activity during the 24 hours prior to testing. Multiple measurements should be performed whthin 2 months, at least one week apart, before making a medical decision about further action. Fasting or non-fasting specimens can be used for TC testing. However, a 12-h fasting specimen is required for TG and recommended for lipoproteins. The subject should be seated for at least 5 minutes before specimen collection. The tourniquet should not be kept on more than one minute during venipuncture. Both serum and plasma are suitable for analysis. Serum is more common and