红斑狼疮 SLE-English-pre 中山大学 内科学.ppt

Systemic Lupus Erythematosus Dr. Ye yujin Rheumatology department The 1st Affiliated Hospital of Sun Yat-Sen University 2009-12-30 Background: Systemic lupus erythematosus (SLE) 1) A chronic, multifaceted inflammatory autoimmune disease 2) Affect every organ system of the body 3) SLE is protean in its manifestations and follows a relapsing and remitting course Epidemiology and Etiology Pathophysiology Clinical features Treatment Epidemiology and Etiology Frequency Worldwide , the prevalence of SLE varies with ethnicity and geographical locations: 70-100 cases per 100,000 population in