慢性阻塞性肺疾病与侵袭性肺曲霉菌病诊治问题思考课件.pptx

慢性阻塞性肺疾病合并侵袭性肺曲霉菌病诊治问题思考;目录;COPD是IA的中危因素之一;临床表现-症状;临床表现-影像学;;;;COPD患者影像学特点;临床表现—GM实验;;激素非粒缺：粒细胞炎？;;激素对免疫的调节作用;激素抑制中性粒细胞与巨噬细胞NADPH活性氧系统;肺组织局部巨噬细胞和中性粒细胞ROS受到部分抑制，局部抵抗力下降;小结;目录;治疗;治疗;This study included 277 patients but only 16 were receiving corticosteroids as predisposing conditions; the majority of the remaining patients had hematological malignancies. Therefore, the evidence of the superiority of voriconazole over amphotericin B for the treatment of IPA in patients with COPD cannot be inferred from this study. ;N Engl J Med 2002;347: 408-15;;;多烯类药物-AmB脂质体衍生物;;ANTIMICROBIAL AGENTS AND CHEMOTHE