探讨肺表面活性物质治疗早产儿呼吸窘迫综合征的临床疗效.docVIP

精品论文 参考文献 探讨肺表面活性物质治疗早产儿呼吸窘迫综合征的临床疗效 马丽 马利勇 　　（银川市妇幼保健院新生儿科 750001） 　　【摘要】目的：探讨肺表面活性物质治疗早产儿呼吸窘迫综合征的临床疗效。方法：选取2012年6月至2013年5月我院收治的早产儿呼吸窘迫综合征患者72例进行分析，按照治疗方法分成观察组和对照组各36例，对照组采用常规治疗，观察组在对照组基础上加用肺表面活性物质治疗，观察两组临床疗效、氧合指数（PaO2/FiO2）、机械通气使用率、吸氧时间、住院时间、并发症发生率和病死率。结果：观察组治疗总有效率明显高于对照组（P＜0.05）；两组治疗后PaO2/FiO2均有明显提高（P＜0.05），且观察组提高水平明显优于对照组（P＜0.05）；观察组机械通气使用率、并发症发生率明显低于对照组（P＜0.05），吸氧时间和住院时间明显少于对照组（P＜0.05）；两组在病死率上比较无明显差异（P＞0.05）。结论：肺表面活性物质治疗早产儿呼吸窘迫综合征能够提高患儿的治愈率，缓解临床症状，降低并发症发生率，安全有效。 　　【关键词】肺表面活性物质 早产儿 呼吸窘迫综合征 　　【中图分类号】R720.5 【文献标识码】A 【文章编号】2095-1752（2014）16-0017-02 　　To investigate the clinical efficacy of pulmonary surfactant in preterm children with respiratory distress syndrome treatment 　　【Abstract】 Objective : To investigate the pulmonary surfactant treatment of respiratory distress syndrome in premature children s clinical efficacy. Methods: June 2012 to May 2013 in our hospital with respiratory distress syndrome in premature children 72 patients were analyzed according to the treatment methods into observation group and the control group , 36 cases in the control group using conventional treatment, the observation group control group based on the use of pulmonary surfactant therapy , clinical efficacy , oxygenation index (PaO2/FiO2), utilization of mechanical ventilation , oxygen time , hospital stay, morbidity and mortality. Results: The total effective rate was significantly higher (P lt;0.05); PaO2/FiO2 after treatment were significantly increased (P lt;0.05), and raise the level of the observation group than the control group (P lt;0.05 ) ; observe the usage of mechanical ventilation , the complication rate was significantly lower than the control group (P lt;0.05), oxygen and hospital stay was significantly less than the control group (P lt;0.05); mortality in the two groups showed no significant difference (Pgt; 0.05). Conclusion: Pulmonary surfactant treatment of respiratory distress syndrome in premature chil