缬沙坦联合苯磺酸氨氯地平治疗高血压的临床效果观察.docVIP

缬沙坦联合苯磺酸氨氯地平治疗高血压的临床效果观察 倪红英 泰兴市燕头社区卫生服务中心 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:探讨缬沙坦联合苯磺酸氨氯地平治疗高血压的临床效果。方法:收治原发性高血压患者110例, 分为对照组和试验组。对照组采用缬沙坦治疗, 试验组采用缬沙坦联合苯磺酸氨氯地平治疗, 比较两组治疗效果。结果:治疗后, 试验组总有效率高于对照组, 舒张压及收缩压水平低于对照组 (P0.05) ;两组不良反应发生率比较, 差异无统计学意义 (P0.05) 。结论:缬沙坦联合苯磺酸氨氯地平治疗高血压的临床效果显著、安全性高。 关键词： 高血压; 缬沙坦; 苯磺酸氨氯地平; Clinical efficacy of valsartan combined with amlodipine besylate in the treatment of hypertension Ni Hongying Yantou Community Health Service Center of Taixing City; Abstract： Objective:To explore the clinical efficacy of valsartan combined with amlodipine besylate in the treatment of hypertension.Methods:110 patients with essential hypertension were selected.They were divided into the control group and the experimental group.The control group was treated with valsartan, and the experimental group was treated with valsartan combined with amlodipine besylate.We compared the therapeutic effects of two groups.Results:After treatment, in the experimental group, the effective rate was higher than that in the control group, and the diastolic blood pressure and systolic blood pressure level were lower than the control group (P0.05) .There was no significant difference in adverse reaction rate between groups (P0.05) .Conclusion:The clinical efficacy of valsartan combined with amlodipine besylate in the treatment of hypertension was significant, and the security was high. Keyword： Hypertension; Valsartan; Amlodipine besylate; 高血压临床表现为不同程度的头晕、头痛、乏力等症状, 精神紧张、过度劳累、情绪波动等均会引起血压升高, 长期发展易引起血管结构及功能改变, 是心脑血管疾病的主要致病因素[1]。本研究在高血压患者中应用缬沙坦与苯磺酸氨氯地平联合治疗, 现报告如下。 资料与方法 2015年5月-2017年4月收治原发性高血压患者110例, 根据就诊时间分为对照组55例和试验组55例。所有患者经血压连续测量进行临床诊断, 舒张压均90 mm Hg, 收缩压均140 mm Hg, 并经检查排除继发性高血压、严重功能障碍者, 确诊为原发性高血压;所有患者均签署知情同意书, 此研究经医院伦理委员会审核批准。对照组男30例, 女25例;年龄45~77岁, 平均 (56.33±5.74) 岁;病程2~12年, 平均 (6.53±1.12) 年。试验组男28例, 女27例;年龄46~78岁, 平均 (57.12±5.44) 岁;病程2~13年, 平均 (6.61±1.08) 年。两组一般资料对比, 差异无统计学意义 (P0.05) , 有可比性。 方法: (1) 对照组口服缬沙坦进行治疗, 80 g/次, 1