年1 月电子学报.pdfVIP

1 Vol. 37 No.1 2009 1 ACTA ELECTRONICA SINICA Jan. 2009 封洲燕, 王 静 ( , 310027) : , , , . :Utah Michigan . , ; , , . : ; ; ; ; ; : TN4, R338 : A : (2009) Progress of Microelectrode Arrays for Brain Signal Recordings FENG houyan, WANG Jing ( College of Biomedical Engineering and Instrument Science, Key Laboratory of Biomedical Engineering of Ministry of Education, Zhej iang Uni ersity, Hangzhou, Zhej iang 310027, China) Abstract : The recording technique of microelectrode arrays provides an ideal means for obtaining the large amount of neu ronal electric activity, simultaneously. The technique has significant impacts on the intensive investigations for the mechanisms of neurons and their networks, as well as on the development of novel neural prosthetic and therapeutic devices.Utah microelectrode and Michigan microelectrode are two major types of rapidly developed electrode arrays that have been used in neural signal detec tions invivo. In this paper,the manufacture,the structure, the feature and the application of both types of electrode are compared. The principles and methodsfor the detection and analysis of neural field potentialsand unit activity by using the electrode arraysare described.In addition,the challenges and further development in electrode fabrication, in neural signal recording and in signal pro cessing are discussed. Key words: microelectrode array; neuroelectrophysiology; structure; application;field potential; spike , 1 , , , . , , , . , 1~ 2 ,