欣母沛联合益母草预防子痫前期剖宫产后出血的疗效评价.docVIP

精品论文 参考文献 欣母沛联合益母草预防子痫前期剖宫产后出血的疗效评价 （北京市怀柔区妇幼保健院，北京，101400） 摘要 目的：探讨欣母沛注射液联合益母草注射液预防子痫前期剖宫产后出血的临床疗效及安全性。方法：104例宫缩乏力性子痫前期剖宫产产妇随机分为研究组与对照组各52例。研究组胎儿娩出后予欣母沛联合益母草治疗，对照组予缩宫素治疗。观察两组产后出血情况及药物不良反应。结果：研究组产后2 h及产后24 h出血量均低于对照组，差异具有统计学意义（P＜0.05）；两组之间年龄、孕周、产次均无统计学意义（P＞0.05）；两组药物不良反应的差异无统计学意义（P＞0.05）。结论：欣母沛注射液联合益母草注射液是防治子痫前期剖宫产后出血的有效方法，安全性高，适于临床应用。 关键词 欣母沛；益母草；子痫前期；产后出血 Therapeutic evaluation of Postpartum hemorrhage by Carboprost tromethamine and Motherwort Injection in Preeclampsia QIU qiu-ming,DU zhao-min,DAI sheng (Maternal and child health hospital of Beijing Huairou, Beijing 101400,China) Abstract Objective :Exploring the therapeutic evaluation and safety of postpartum hemorrhage by Carboprost tromethamine and Motherwort Injection in preeclampsia .Methods 102 cases of preeclampsia woman were randomly divided into２groups，54 cases in research group were treated with Carboprost tromethamine and Motherwort Injection,54 cases in control group were treated with oxytocin. The two groups were observed the occurrence of postpartum hemorrhage and safety.Results The amount of bleeding postpartum research group 2H and 24h were significantly lower than those of control group （Plt;0.05）.There was no significant differencein in mean age,gestational weeks and delivery times among two groups（Pgt;0.05）.In same way,Adverse drug reactions compared in two groups was no significant differencein （Pgt;0.01）. Conclusion Carboprost tromethamine and Motherwort Injection on prevention of postpartum hemorrhage in preeclampsia has a significant effect,which can be popularize safety in clinic treatment. key words Carboprost tromethamine ;Motherwort Injection;Preeclampsia;Postpartum hemorrhage 产后出血是产科常见并发症之一，是指胎儿娩出的24 h内，产妇出血量超过500 mL[1]。有资料统计，约有2%~3%的产妇分娩后可发生产后出血，该并发症在中国产妇死亡原因中高居首位[2]。子痫前期（preeclampsia,PE）是导致的产后出血是产妇死亡率升高的重要原因，该疾病造成产后出血的常见原因有胎盘因素、子宫收缩乏力、软产道损伤及凝血功能障碍等，所以强化子宫收缩功能是治疗子痫前期产妇产后出血的主要措施。近年来，临床上防治子痫前期产妇产后出血的药物层出不穷，但单纯性应用缩宫素疗效欠佳，严重者诱发难治性出血，需要应用髂内动脉结扎术、宫腔纱条填塞，甚至子宫切除术来治疗，给产妇的身心造成了极大的伤害