胃食管反流病维持治疗方式的影响因素分析.docVIP

精品论文 参考文献 胃食管反流病维持治疗方式的影响因素分析 孙怡 　　（遂宁市中心医院 四川遂宁 629000） 　　【摘要】目的：探讨胃食管反流病维持治疗方式的影响因素,从而找出合适的治疗方法。方法：随机选取自2010年1月至2014年5月间消化内科门诊诊治的200名患者,作为研究对象，并随机分为实验组（100例）和对照组（100例），实验组患者采用按需治疗或连续治疗的方式，患者均需要连续用药，若停止药物则在一周内复发。对照组则选取停药后仍不会对患者的生活造成影响的患者。结果：经过一段时间的治疗后，在病程与Demeester积分的比较中，实验组患者明显优于对照组，差异具有统计学意义（P＜0.05）。同时在治疗前对实验组患者进行内镜检查时发现有67例被诊断为II-III级RE患者，对照组中则有8例被诊断为II-III级RE患者，差异亦具有统计学意义（P＜0.05）。治疗效果与下食管括约肌松弛食管炎的严重程度，病程等之间有着密切的关系。结论：对于解剖结构异常、食管功能低下，反流现象严重的年老患者需要进行按需治疗和连续用药治疗，并在临床中取得了良好的效果，具有重要的意义。 　　【关键词】胃食管反流；维持治疗方式；影响 　　【中图分类号】R45 【文献标识码】A 【文章编号】1007-8231（2015）08-0045-03 　　【Abstract】Objective To investigate the effect of gastroesophageal reflux disease treatment to maintain influence factor, so as to find out the suitable treatment method. Methods Randomly selected from 200 patients admitted from 2010 January to 2014 May, as the research object, and randomly divided into the experimental group (100cases) and control group (100 cases), the experimental group were treated with on-demand therapy or continuous treatment, patients need continuous medication, if stop drug relapse within a week. The control group was selected after the withdrawal will not cause unnecessary impact on the lives of patients with. Results After a period of time after treatment, in comparison with the Demeester integral in the course of disease, the patients in the experimental group was significantly better than the control group, the difference was statistically significant (P lt; 0.05). At the same time found in endoscopy for patients in the experimental group with 67 cases were diagnosed as II-III grade RE patients, in the control group with 8 cases were diagnosed as II-III stage RE patients, the differences were statistically significant (P lt; 0.05). In the curative effect, and the severity of lower esophageal sphincter relaxation esophagitis, there is a close relationship between the course of disease. Conclusion The abnormal anatomy, esophageal dysf