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COMMUNICATION /chemcomm | ChemComm PAMAM dendrimers for efficient siRNA delivery and potent gene silencing{ Jiehua Zhou,a Jiangyu Wu,ab Nadia Hafdi,c Jean-Paul Behr,d Patrick Erbacherc and Ling Peng*ab Received (in Cambridge, UK) 30th January 2006, Accepted 3rd May 2006 First published as an Advance Article on the web 10th May 2006 DOI: 10.1039/b601381c Genuine, nondegraded PAMAM dendrimers self-assemble successive bonds from the center amine (Sche