杀菌剂毒理学分论PPT.ppt

* Manozeb (代森锰锌) Mancozeb is used to protect many fruit, vegetable, nut and field crops against a wide spectrum of fungal diseases, including potato blight (马铃薯晚疫病), leaf spot, scab (on apples and pears), and rust (on roses). It is also used for seed treatment of cotton, potatoes, corn, sorghum, peanuts, tomatoes, flax, and cereal grains. * Manozeb (代森锰锌) It is used as a protective fungicide (to prevent fungal growth) and in foliar and seed treatments to control a wide range of pathogens in field crops, fruits, ornamentals and vegetables. 作用机理:抑制丙酮酸的氧化. * Chlorothalonil (百菌清) Chlorothalonil is a broad-spectrum organochlorine fungicide used to control fungi that threaten vegetables, trees, small fruits, turf, ornamentals, and other agricultural crops. Chlorothalonil is a non-systemic foliar fungicide. * Chlorothalonil (百菌清) Regulatory Status: Chlorothalonil is classified as a General Use Pesticide (GUP) by the U.S. -EPA. It is classified as toxicity class II - moderately toxic, due to its potential for eye irritation. Chlorothalonil containing products have a range of Signal Words, including WARNING, CAUTION, and DANGER. * Chlorothalonil (百菌清) Toxicological Characteristics Technical chlorothalonil is a severe eye irritant, moderately toxic via inhalation, and of low toxicity via oral and dermal exposures. * Chlorothalonil (百菌清) Mechanism of pesticidal action: The mode of action of chlorothalonil involves its reaction with thiol groups of the pathogenic fungis enzyme systems. * Chlorothalonil (百菌清) Mechanism of pesticidal action: In control of mildew in paints, it conjugates and depletes thiols from germinating fungal cell, leading to disruption of glycolysis and energy production, fungistasis, and fungicidal action. * Chlorothalonil (百菌清) Chlorothalonil has a multiple site mode of action, making the development of resistance much less likely. No resistance has been confirmed to date, making chlorothalonil an excellent component of a resistance mana