组织多普勒成像联合MVF、PVF在吸毒者左心室舒张功能中的应用及评价.docVIP

组织多普勒成像联合MVF、PVF在吸毒者左心室舒张功能中的应用及评价 　　[摘要] 目的 探?组织多普勒成像联合评价吸毒者左心室舒张功能的临床价值。 方法 选取89例吸毒患者分为三组及健康对照59例为研究对象。组织多普勒成像及MVF，PVF，测量二尖瓣E峰、A峰速度及速度之比（E/A）；二尖瓣E峰减速时间DT；肺静脉收缩波、舒张波速度（S、D）；肺静脉收缩波，舒张波流速之比（S/D）；肺静脉心房收缩波速度（AR）、持续时间（Adur）。 结果 （1）吸毒年龄小，吸毒时间长，左室舒张功能越差，左室壁增厚，左房、室增大；（2）MVF参数： 对照组与吸毒组各组间随各组心功能逐渐增加E/A未见逐级递减关系，分析原因吸毒组B、C、D组E/A三类构成比不同（1；2）分别为11/31/0、31/18/1、6/4/7； （3）PVF参数：吸毒组各组间B、C、D随各组心功能等级逐渐增加，S波速度、S/D数据递减，D波速度、AR、Adur数据递增。对照组A 与吸毒B组之间除S波速度外均无明显差异；（4）组织多普勒成像参数：吸毒组各组间B、C、D组随各组心功能等级逐渐增加，e，e/a递减，a逐渐升高（P 　　[关键词] 组织多普勒成像；二尖瓣血流；肺静脉血流；左心室舒张功能 　　[中图分类号] R540.4 [文献标识码] B [文章编号] 1673-9701（2017）12-0129-04 　　[Abstract] Objective To evaluate the clinical value of combined evaluation of tissue left ventricular diastolic function by Doppler imaging in drug users. Methods 89 drug users were selected and divided into three groups and 59 healthy controls were selected as the study subjects. Tissue Doppler imaging and MVF， PVF were conducted；mitral valve E peak， A peak velocity and velocity ratio（E/A）； mitral valve E peak deceleration time DT； pulmonary vein contraction wave， diastolic wave velocity（S， D）； ratio of pulmonary vein contraction wave velocity to diastolic wave velocity （S/D）； pulmonary venous atrial contraction wave velocity （AR） and duration （Adur） were measured. Results （1）The younger the age of using drug and the longer the time of drug use， and the worse the left ventricular diastolic function. The left ventricular wall was thickening， and the left atrium and the left ventricle were larger； （2） MVF parameters： There was no gradual decline in E/A along with the increasing cardiac function in the control group and drug use group. The composition ratio of three types of E/A was different in drug use group B， C and（1； 2）， 11/31/0， 31/18/1，6/4/7 respectively； （3）PVF parameters：The PVF parameters were gradually increasing along with the cardiac function in drug use group B， C， and D. S-wave velocity， and S/D were decreasing， and D-wave velocity， and AR， Adur were increasing.Th