过滤芯完整性测试资料方案PPT.pptVIP

Filter Integrity test;Content 讲座目录;What is filter integrity? 什么是滤膜完整性? ;Why Integrity Test? 为什么做完整性测试?;Regulations about integrity test 法规中对完整性测试的规定;Type 分类;Destructive vs. Non-destructive Testing 破坏性和非破坏性测试 ;Integrity Testing Correlations 完整性测试关联;What Non-Destructive Integrity Tests are Available? 何种非破坏性测试合适?; Bubble point is the pressure at which gas displaces liquid from the largest set of filter pores and flows rapidly through the filter 起泡点是气体从湿润的最大膜孔挤出液体快速流出时的压力 Bubble point indicates the magnitude of the forces holding liquid in the filter structure 起泡点显示过滤结构内保持液体的力的大小 The oldest non-destructive integrity test 最传统的非破坏性测试;Bubble point test 泡点测试;Bubble Point Test Applicability 起泡点测试适用性;Bubble Point Equation起泡点等式;Effect on bubble point test 泡点的影响因素;Contact angle 接触角的影响; Two sterilizing grade filters with identical bacterial retention claims and performance have the following minimum bubble point specifications: 两种无菌过滤膜用同一细菌截留有下列最小的起泡点规格: Durapore? PVDF CVGL = 50 psig Charged Durapore? PVDF CCGL = 40 psig A sterilizing grade filter has is the following minimum bubble point specifications: 一种无菌过滤膜有下列最小的起泡点规格: Water = 50 psig 70/30 IPA = 18.5 psig Higher bubble point test values do not mean better filters 高起泡点值并不是意味好的过滤膜 Check the filter manufacturers validation guide for the destructive / non-destructive integrity test correlation, integrity testing technique and bacterial challenge method 检查过滤膜制造商对破坏性/非破坏性完整性测试关连的验证文本,完整性测试技术和细菌挑战理论 膜没有洗干净可能影响到接触角而导致完整性测试失败;Diffusion Testing Introduction 扩散流测试介绍;Diffusion test 扩散流测试;Diffusion Testing Equation扩散测试方程;A Reason for Diffusion Testing 什么情况下采用扩散测试;Diffusion Test Applicability 扩散测试适用性;Factors Affecting Diffusion Tests 扩散测试的影响因素;Polypropylene cartridge tested with nitrogen at 18.8 psig (1.3 bar )聚丙烯过滤器用氮气(18.8psig)测试 Acetone 390 ml/min IPA 120 ml/min MESSAGE: Changing solvents changes diffusional flow Pure organic solvents have high diffusional flow 改变溶剂可改变扩散流速,纯溶剂有较高的流速 Can mask bubble