评价泮托拉唑治疗２型糖尿病合并胃溃疡的临床效果.docVIP

精品论文 参考文献 评价泮托拉唑治疗２型糖尿病合并胃溃疡的临床效果 康栓平 　　山西省柳林县人民医院消化内科　山西　柳林　０３３３００ 　　【摘要】　目的　研究分析泮托拉唑治疗２型糖尿病合并胃溃疡的临床疗效.方法　回顾性分析我院于２０１４年２月~２０１５年３月收治的１００例２型糖尿病合并胃溃疡患者的病历资料,随机的分为对照组和观察组.对照组中的５０例患者应用基础治疗,观察组中的患者基础治疗的基础上应用泮托拉唑治疗,对比分析两组患者的胃溃疡愈合情况以及临床疗效.结果　对照组患者的根除率为６９．２％,观察组患者的根除率为８５．７％.观察组患者的根除率和对照组比较,明显较高,P＜０．０５,有统计学意义.观察组中的患者,２５例痊愈,２４例好转,１例无效,临床治疗总有效率为９８％.对照组中的患者,２１例痊愈,１９例好转,１０例无效,临床治疗总有效率为８０％.对照组患者的临床疗效和观察组比较,观察组临床疗效显著,P＜０．０５,有统计学意义.结论　糖尿病合并胃溃疡患者应用泮托拉唑治疗,可以有效改善患者的溃疡症状和糖尿病症状,临床疗效显著,有一定的安全性和可行性,值得临床推广应用. 【关键词】　泮托拉唑;　２型糖尿病;　胃溃疡;　临床疗效窗体顶端【Abstract】　Objective:Toinvestigatetheclinicalefficacyoftype２diabeteswithgastriculcertreatmentpantoprazole．Methods:AretrospectiveanalysisofmedicalrecordsofthehospitalinFebruary２０１４~ March２０１５weretreated１００casesoftype２diabetesmellituspatientswithgastriculcerwererandomlydividedintocontrolgroupandobservationgroup．５０casesinthecontrolgrouppatientsappliedbasicapplicationpantoprazoletreatmentbasedobservationgroupofpatientstreatedonthebasisofcomparativeanalysisofthetwogroupsofpatientswithgastriculcerhealingandclinicalefficacy．RESULTS:Theeradicationratewas６９．２％inthecontrolgroupofpatientsobservedinpatientseradicationwas８５．７％．EradicationrateofpatientsintheobservationgroupandthecontrolgroupwassigＧnificantlyhigher,P ＜０．０５,statisticallysignificant．Patientsintheobservationgroup,２５casescured,２４casesimproved,１casesineffective,clinicaltotaleffecＧtiveratewas９８％．Patientsinthecontrolgroup,２１casescured,１９casesimproved,１０casesineffective,thetotaleffectiveclinicaltreatmentwas８０％．TheconＧtrolgroupofpatientsclinicalefficacyandobservationgroup,theobservationgroupsignificantclinicaleffect,P ＜０．０５,statisticallysignificant．Conclusion:Thecombinedapplicationofulcerpatientswithdiabetespantoprazoletreatmentcaneffectivelyimprovethesymptomsofulceranddiabetessymptoms,clinicaleffectissignifi【cKaenytw,otrhdesre】arecertainsafetyandfeasibility,worthyofclinicalapplication． 　Pantoprazole;　Type２diabetes;　Ulcer;　Clinicalefficacy 【中图分类号】R５７１ 【文献标识码】B 　　【文章编号】１００８－６３１５(２０１５)１０－０１５２－０２　　 　　２型糖尿病患者机体的血