评价高频振荡通气（HFOV）治疗常频机械通气（CMV）失败新生儿持续肺动脉高压的效果及安全性.docVIP

精品论文 参考文献 评价高频振荡通气（HFOV）治疗常频机械通气（CMV）失败新生儿持续肺动脉高压的效果及安全性 怀化市第一人民医院 湖南怀化 41800 摘要：目的：分析和研究高频振荡通气（HFOV）治疗常频机械通气（CMV）失败新生儿持续肺动脉高压的效果及安全性。方法：选取2013年4月—2015年4月经常频机械通气治疗失败患儿21例，采用高频振荡通气治疗，将其治疗方法与效果进行回顾性的分析与总结。结果：治疗效果：21例患儿中治愈19例，治愈率为90.5%；死亡3例，死亡率为9.5%。血气指标检测值变化情况：患者治疗24小时后、48小时后氧分压、血氧饱和度、pH值均高于治疗前；二氧化碳分压、吸入氧浓度均低于治疗前P＜0.05。并发症发生情况：脑室内出血1例，发生率为4.8%。结论：将高频振荡通气应用于常频机械通气失败新生儿持续肺动脉高压患儿治疗中，其能够有效改善患儿氧合状态，减少呼吸机对机体损伤程度，对促进患儿病情转归及提高治疗效果均具有重要作用。 关键词：高频振荡通气；常频机械通气；新生儿；持续肺动脉高压 Abstract Objective：To analyze and study high-frequency oscillatory ventilation（HFOV）therapy is often the frequency of mechanical ventilation（CMV）fail newborns with persistent pulmonary hypertension of the efficacy and safety.METHODS：April 2013 - April 2015 the frequency of mechanical ventilation in children often fails 21 cases，the use of high frequency oscillatory ventilation therapy，treatment methods and their effect retrospectively analyzed and summarized.Results：The treatment：21 patients were cured in 19 cases，the cure rate was 90.5%；3 patients died，the mortality rate was 9.5%.Detect changes in blood gas values：patients after 24 hours，48 #8203;#8203;hours after the oxygen partial pressure，oxygen saturation，pH values #8203;#8203;were higher than before treatment；carbon dioxide partial pressure，inspired oxygen concentrations were lower than before treatment，P lt;0.05.Complications were：intraventricular hemorrhage in one case，the rate was 4.8%.Conclusion：The high-frequency oscillatory ventilation applied normal frequency of mechanical ventilation in children with persistent pulmonary hypertension of the newborn failure treatment，which can improve the oxygenation status of children and reduce the extent of damage to the body breathing machine，and the promotion of children with the disease outcome improve treatment have an important role. Key words high frequency oscillatory ventilation；normal frequency ventilation；newborns；persistent pulmonary hypertension 新生儿持续性肺动脉高压是指在各种因素影响下使患儿肺部肌层增生或动脉痉挛而致肺动脉阻