b型流感嗜血杆菌-英文课件PPT.ppt

Haemophilus influenzae type b  Using vaccines to measure disease burden: A Tale of Two Studies;Hib - characteristics;Hib disease;Gambian PRP-T trial;Did the vaccine actually prevent pneumonia?;What did the Gambia trial tell us about the epidemiology of Hib pneumonia in West Africa?;Conclusions;Why are Hib vaccines not used all over the world?;Asia;What is going on in Asia?;First Asian Hib Meeting – Bali 1996;Lombok Vaccine Probe Study Design;Vaccine-preventable Hib disease incidence;Primary outcome of study;Secondary outcomes of study;Vaccination of children;All incidences are per 100,000 child-years;All incidences are per 100,000 child-years;All incidences are per 100,000 child-years;All incidences are per 100,000 child-years;Published rates of Hib meningitis (Children under 5 years – per 100K person-years);Mortality rates are per 100,000 child-years;Mortality rates are per 100,000 child-years;Conclusions;Comparison of Gambia and Lombok Results