中国结核感染现状（英文版）PPT.ppt

Latent Infection of Tuberculosis in China HUASHAN HOSPITAL, FUDAN UNIVERSITY, Shanghai, China Wenhong Zhang, M.D PhD. ;TB: A leading infectious killer- top 3 infectious killer; The New Tuberculosis;TB Chemotherapy: THE Effective TB Control;DOTS-The Best TB Therapysince 1991;Prevalence of Smear Positive Tuberculosis in China;Incidence of tuberculosis according to the report from China CDC;Factors contribute to tuberculosis reemerging in China;HIV infected Tuberculosis Cases 1/100,000 population in China;Latency;Dormant or Persistent Bacilli; New TB cases are driven by the reservoir of latently infected people. If we want to stop active TB cases, we need to eliminate this reservoir of infection. This “hidden epidemic” of people infected with latent TB is enormous. The growth in latent TB is becoming a clinical time bomb. We need to defuse this bomb by increasing our efforts to identify and treat latently infected people. ;Epidemiology of latent infection in the world;;Shortage of TST;Factors leading to False-Positive TST Reactions;T SPOTTM detect INF-r released by specific T cells;;;2 commercial Kit available for detecting latent or active tuberculosis;T-cell based assay is recommended for detecting infection of M. Tb;;The strategic for treating latent infection of tuberculosis in China?;Lifetime Risk of Reactivation Tuberculosis;Latent infection of tuberculosis in China: Treat or not Treat?