贝那普利联合氨氯地平治疗原发性高血压的临床分析.docVIP

精品论文 参考文献 贝那普利联合氨氯地平治疗原发性高血压的临床分析 张敏 　　（浙江省杭州市余杭区瓶窑镇社区卫生服务中心 全科门诊 浙江 杭州 311115） 　　摘要：目的：贝那普利联合氨氯地平治疗原发性高血压的临床疗效。方法：回顾性分析我社区2014年1月~2015年1月期间内收治的高血压患者90例的临床资料，随机分为对照组和观察组，对照组采取苯磺酸氨氯地平片口服治疗，观察组采取贝那普利联合氨氯地平治疗，比较两组患者的血压及其临床疗效。结果：观察组总有效率为95.55%，对照组总有效率为77.78%，观察组临床疗效显著优于对照组，差异有显著性（plt;0.05）;治疗后两组患者的舒张压和收缩压均显著低于治疗前，差异有显著性（plt;0.05）；治疗后，观察组患者的舒张压和收缩压均显著低于对照组，差异有显著性（plt;0.05）。结论：贝那普利联合氨氯地平治疗原发性高血压疗效确切、不良反应小，安全可靠，值得在临床上合理推广应用。 　　关键词： 贝那普利； 氨氯地平； 原发性高血压 　　Abstract： Objective:The clinical efficacy of essential hypertension benazepril and amlodipine treatment. Methods: A retrospective analysis of our hospital in the January 2014 - January 2015 hypertensive patients treated during the clinical data of 90 cases were randomly divided into control group and observation group and control group taking amlodipine besylate tablets oral treatment observation group taking benazepril and amlodipine treatment, blood pressure and clinical efficacy of two groups were compared. Results: The total effective rate was 95.55% in the control group, the total effective rate was 77.78%, the clinical efficacy of the observation group was significantly better than the control group, the difference was significant (p lt;0.05); after treatment, both groups diastolic and systolic pressure were significantly lower than before treatment, the difference was significant (p lt;0.05); after treatment, observation group of patients with diastolic and systolic blood pressure were significantly lower than the control group, the difference was significant (p lt;0.05).Conclusion:benazepril and amlodipine treatment of essential hypertension is effective, side effects, safe and reliable, worthy of clinical reasonable application. 　???Keywords：benazepril; amlodipine; essential hypertension 　　原发性高血压是心脑血管疾病的主要危险因素。降压治疗已成为预防心脑血管疾病的重要策略，长期有效地控制血压能够明显减少心脑血管疾病发生的危险。贝那普利属血管紧张素转换酶抑制剂（ACEI），氨氯地平属钙离子拮抗剂(CCB)，皆为临床常用于治疗原发性高血压的药物。本组探讨贝那普利联合氨氯地平治疗原发性高血压的疗效，效果显著，现将报告如下。 　　1.资料与方法 　　1.1一般资料 本组全部患者均为我社区2014年1月~2015年1月期间内收治的高血