贵州省2013年疑似预防接种异常反应监测分析.docVIP

精品论文 参考文献 贵州省2013年疑似预防接种异常反应监测分析 徐飞 张大勇 杜雯 张丽 冯军 王涛 　　（贵州省疾病预防控制中心免疫规划所 贵州贵阳 550004） 　　【摘要】目的：分析贵州省2013年疑似预防接种异常反应（AEFI）的发生特征，评价AEFI监测系统运转状况、国家免疫规划疫苗安全性。方法：通过AEFI监测系统收集贵州省2013年1月1日至2013年12月31日报告的AEFI个案数据，采用描述性方法对相关指标进行流行病学分析。结果：贵州省2013年共报告AEFI个案285例，报告县覆盖率为98.9%，48h内报告率为92.28％，48h内调查率为97.06％。一般反应占88.07％，异常反应占8.42％。AEFI病例中le;1岁的儿童占62.81%；各月均有AEFI病例报告，主要集中在7～9月，占45.26％。接种无细胞百白破疫苗和白破疫苗后报告的AEFI病例最多，分别占32.75%和11.97%。临床诊断分类居前三位的是发热/红肿/硬结（占60.7%）、其他（26.32%）和过敏性皮疹（5.96%）。结论：贵州省AEFI发生主要集中在le;1岁的小年龄组，该部分儿童应作为预防接种工作人员关注的重点。 　　【关键词】疑似预防接种异常反应；监测；疫苗 　　【中图分类号】R18 【文献标识码】A 【文章编号】1007-8231（2016）09-0013-02 　　 Study on the Surveillance of Adverse Events Following Immunization of Guizhou Province in 2013 　　 Xu Fei,Zhang Dayong,Du Wen,Zhang Li,Feng Jun,Wang Tao.Center for Disease Control and Prevention of Guizhou,Guiyang 550004,China 　　【Abstract】Objective To analyze occurrence features of adverse events following immunization(AEFI) and evaluate the operating quality of AEFI information management system and the immunization safety in Guizhou Province in 2013.Method AEFI data reported from January 1,2013 to December 31,2013 were collected through the National AEFI Information Management System.The descriptive method was used to analyze the AEFI occurrence features.Results 285 cases of AEFI were reported in 2013,the proportion of counties with reporting was 98.9%,Proportion of cases reported within 48h was92.28%,and the proportion of cases investigated within 48h was 97.06%.88.07% AEFI cases were common,minor reactions,and 8.42% were rare,serious reactions.Cases le;1 year old accounted for 62.81%;AEFI cases were reported in every month, mainly in July to September, accounting for 45.26%.32.75% and 11.97% of the AEFI cases were related to DpaT and DT. The top three Clinical classification were fever/swelling/induration (60.7%), others (26.32%) and allergic rashes (5.96%). Conclusion AEFI cases occurred mainly in le;1 year old,therefore,T