血型与ardsPPT.pptVIP

严重创伤及脓毒血症后ARDS风险或与血型相关;严重创伤及脓毒血症后ARDS风险或与血型相关;ABO glycosyltransferases catalyze antigen modifications on various glycans and glycoproteins and determine the ABO blood types.? ABO糖基转移酶能促进各种多聚糖和糖蛋白抗原的改变，并决定人们的ABO血型。;;We conducted prospective cohort studies in two populations at an urban tertiary referral, level I trauma center. Critically ill patients (n 5 732) presenting after major trauma were followed for 5 days for ARDS development. Additionally, 976 medical patients with severe sepsis were followed for 5 days for ARDS. Multivariable logistic regression was used to adjust for confounders. 该项前瞻性队列研究纳入人群包括在一家三级城市的转诊中心和Ⅰ级创伤中心内就诊的2类患者：732例严重外伤后的危重患者及976例患有严重脓毒症的内科患者。研究人员对这些患者分别进行了为期5天的随访，以观察其ARDS的发生状况；并采用多变量logistic回归分析对相关混杂因素进行了校正。 ;Blood type A is associated with an increased risk of ARDS in white patients with major trauma and severe sepsis. These results suggest a role for ABO glycans and glycosyltransferases in ARDS susceptibility. 该研究显示，对于美国白种人而言， A型血与严重创伤及脓毒症患者ARDS风险的增加相关。这表明ABO多聚糖和糖基转移酶对某些患者的ARDS易感性有一定影响。