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- 2018-02-04 发布于江苏
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ANTIBIOTIC;PROBLEM
there are many chemicals that are lethal to bacteria (e.g. cyanide), but cannot be used to cure because they are lethal to the host as well
problem is to find substances that attack a metabolic pathway found in bacterium but not in host; first known use of antibiotics - ancient Chinese (2,500 years ago)
ancient Egyptians and Greeks used molds and plants to treat infections;Penicillin;Accidental discovery
On 3 September 1928, Fleming returned to his laboratory having spent August on vacation with his family. Before leaving he had put his cultures of staphylococci in a c
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