时间药理学和时间治疗学讲解课件.pptVIP

2018-2-6 1 时间药理学与临床合理用药 CHRONOPHARMACOLOGY AND RATIONAL MEDICATION 2018-2-6 2 时间药理学Chronopharmacology 研究药物的体内过程和药物效应与机体生物周期的相互关系 生物周期性(bioperiodicity) 机体的功能状态随时间推移所呈现的规律性变化，包括近日节律 (昼夜节律circadian rhythm)和近年节律(circannual rhythm) 2018-2-6 3 The distinguish on the effect of drug while using in different time The same disease, same medicine, same dose, take in different time of a day, there are different effect and toxicity. The degree of the difference may be twofold, or even decades times. 2018-2-6 4 The revolving circling movement of time which can be comp