有机合成讲义CARBONIUM2.pptVIP

c. Reactions between ketones and acid chlorides or anhydrides d. Reactions of 2-methylpyridine and related compounds Question: can not undergo the corresponding acid-catalyzed reaction, please make a reasonable explanation. The following compounds Pinacyanol (cation) 5. Mannich reaction Mannich base Mechanism: Stuctural requisites in the reactants Amine: R2NH, RNH2, NH3 Aldehydes Other related Mannich reactions: b-Dibasic acids, b-cyano-acids, b-keto-acids,etc. 2-Methylpyridine and related compounds Phenols Furan, pyrrole, indole, and their derivatives Modifications of the Mannich reaction