猪囊尾拗病cysticercosis——神经病学双语课件.ppt

Cerebral Cysticercosis In the central and south America and in parts of Africa and the Middle East,south-east Asia. This is the larval or intermediate stage of infection with the pork tapeworm T. Solium. affects the brain in 60~90%of cases Pathogenesis Clinical manifestation 1 cerebral parenchyma type:seizures,focal neurologic signs,encephalitis 2 subarachnoid space type:headache,hydrocephalus,meningitis 3 intraventricle type:Brun’s sign middle foramen of the fourth ventricle 4 spinal cord type. Laboratory findings The serum antibody to cyst worm is usually positive using ELISA or Western blot. CSF:normal;lymphocyte,pressure,protein increase CT,MRI:contrast-enhanced mass lesions with surrouding edema,intracerebral calcification,ventricular enlargement. Diagnosis History CT,MRI antibody the presence of multiple calcified lesions in the thigh, leg, and shoulder muscles . Treatment and prevention The usual dose of praziquantel is 50 mg/kg of body weight, given orally daily for 1 5 to 30 days. Albendazole (5 mg/kg tid for 15 to 30 days), an alternative treatment, is believed by some to be more effective. Initially, treatment may seem to exacerbate neurologic symptoms, with an increase in cells and protein in the CSF.corticoid and mannitol may be useful. Surgery * * Zheng Dongming Food contaminated by eggs of T. solium. Retrograde infection of proglottid Anus to oral Onchosphere in duodenum All over the body by blood circulation cysticercus cellclosae