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Fontan术后蛋白丢失性肠病的机制和治疗研究综述.PDF
254 M olecular Cardiology of China, August 2009, Vo.l 9 No. 4( SerialNo. 47)
# #
ontan
张家芬 花中东 沈向东
= ( PLE) ontan, ontan PLE
PLE
, PLE , ontan PLE
= ontan; ( PLE); ;
P rote in- losing en teropathy after th e F on tan operation : m echan ism s andth erap ies ZHANG Jia-f en,
H UA Zhong-dong, SHEN X iang-dong. P ediatric Surgery Departmen,t uw aiH osp ital, P eking UnionM ed ical
College and Chinese Academy of M edical Sciences, Beij ing, 10037, China
= A bstract Protein-losing enteropathy ( PLE) is one of the comp licationsw ith sign ificant m orb id ity
and mortality seen after the ontan operation. A t present, there is no effective therapy for th is com plication.
A fter summ arizing the characteristics of the pathophysiology and the m esentery pathological anatomy of PLE
after the ontan procedure, especially the characteristics of the casesw hich responded well to certain thera-
p ies, to investigate the probablem echanism s, the risk factors of the incidence of PLE after the ontan opera-
tion and to give treatm ent suggestions.
= K ey w ords ontan operation; Protein-losing enteropathy ( PLE); M echan ism; Therap ies
15 mm Hg,
1
PLE , PLE
[ 2]
( PLE) ontan , PLE? O strow AM
, 62 ontan 6,
, , PLE7,
A1, ,
PLE 2 9, 3. 7
[ 1] , PLE
PLE,
, PLE
37% TN -A, CRP
2
PLE PLE ,
2. 1病理生理研究: ontan PLE PLE S C
, : O strow AM ontan PLE
,
, , ,
, , CR
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