2004间充质干细胞特性与应用前景.pdf

16 3 Vol. 16, No. 3 2004 6 Chinese Bulletin of Life Sciences Jun., 2004 1004-0374(2004)03-0135-03 200433 Q 8 1 3 A The properties and application potentials of mesenchymal stem cell WU Min-Juan, LIU Shan-Rong, LIU Hou-Qi (Department of Histology and Embryology, Academy of Basic Medicine, Second Military Medical University, Shanghai 200433, China) Abstract: Mesenchymal stem cells (MSCs), which possess the basic properties of the common stem cell, are the progenitor cells in the mesoderm development. In the different conditions and specific developmental stages, MSCs can differentiate into varieties of tissues, for instance, chondrocytes, osteoblast, skeletal myoblast, neuron cells, vascular endothelial cells, etc. There are still a few MSCs in adult organs or tissues for their regeneration and repair. Easier to be isolated and cultured, MSCs have become attractive as seed cells for stem cell biological engineering. In view of their committed induction to differentiate into many sorts of cells and tissues, MSCs offer tremendous potentials for clinical application and basic research. Key words: mesenchymal stem cell; differentiation; clinical application 20~30 [3]