[医药卫生]B细胞淋巴瘤诊疗规范-昆明.ppt

Inclusion criteria CD20+ follicular NHL; Ann Arbor stage III or IV (classes B, C and D) No previous systemic antilymphoma treatment WBC 25 x 109/L No CNS involvement Additional standard inclusion criteria 美罗华联合各种化疗一线治疗可延FL总生存：三个关键的临床试验 无论那种化疗方案，美罗华组的总生存和无病生存均能明显延长 98年随着美罗华问世后，FL患者的OS有了显著改善 * Actuarial survival curves for patients with low-grade NHL treated at Stanford University from 1960–1976, 1976–1987, and 1987–1996 are essentially indistinguishable, which shows that the widespread use of single-agent or multi-agent chemotherapy or combined modality therapy has not had a significant impact