宫颈特殊染色技术对子宫颈癌及宫颈上皮内瘤变初筛-现代生物医学进展.PDFVIP

1074 现代生物医学进展 Progress in Modern Biomedicine Vol.15 NO.6 FEB.2015 doi: 10.13241/ki.pmb.20 15.06.017 宫颈特殊染色技术对子宫颈癌及宫颈上皮内瘤变初筛的临床研究 耿 俐 王晓宁 王改琴 崔 琨 李燕华 解放军第三医院妇产科 西宝鸡721000 ） 。 1963 摘要 目的：探讨宫颈特殊染 技术筛查方法对宫颈癌及癌前病变的筛查意义 方法：本研究通过对 例就诊我院妇科门诊的 (FRD) ，分析FRD 。 1963 患者进行宫颈特殊染 检查 ，以组织病理学检查结果为标准 宫颈特殊染 的临床意义 结果： 例患者行宫 CINI 80.77% CINII81.25% 颈特殊染 检查及对初筛阳性患者行阴道镜下活检，根据活检病理结果进行分析， 阳性率 ， ， CINIII100% ，侵润癌 100% ，总阳性率90.50% 。结论：利用亚甲蓝显 和醋酸白化反应双重定位及指示，不仅可提高宫颈癌及癌 前病变的检出率，而且操作简便，判读容易，结果快速，成本低廉。 ： 关键词 宫颈特殊染 技术；初筛；子宫颈病变；临床研究 R737.33 A 1673-6273 2015 06-1074-02 中图分类号： 文献标识码： 文章编号： （ ） Clinical Study of Special Staining Technique in Preliminary Screening of Uterine Cervix Cancer and Cervical Intraepithelial Neoplasia To investigate the screening significance of special staining technique for cervical cancer and precancerous lesions. 1963 cases of gynecological outpatients undergoing cervical special staining (FRD) in our hospital were studied, the result of shistopathological examination was employed as the standard, the clinical significance of FRD in cervical special staining was analysed. Patients with positive screening result in cervical special staining took further colposcopy biopsy, according to biopsy pathological results, the positive rate of CINI was 80.77%, 81.25% for CINII, 100% for CINIII, and 100% for invasive cancer, the total positive rate was 90.50 %. Using dual localization and indication of Methylene blue and acetic acid bleaching reaction can improve the detection rat