肠道菌群紊乱与疾病教学教材演示幻灯片.pptVIP

肠道菌群紊乱与疾病;肠道细菌的建立及功能;肠道菌群 Gut Microbiota ;人体消化道细菌分布;人体结肠菌群结构;肠道菌群 Gut Microbiota;;益生菌 Probiotics;;“卫生”学说 “hygiene hypothesis”。;结肠菌群与结肠癌的关系;结肠癌 Colorectal Cancer;肠道细菌与结肠癌危险因素相关;无菌小鼠 Germ-free (GF) mouse ;The gut microbiota as an environmental factor that regulates fat storage Fredrik Backhed et al.;Obesity alters gut microbial ecology（？）Ley et al.;Early differences in fecal microbiota composition in children may predict overweightKalliomaki et al.;结肠菌群与结肠黏膜免疫、炎症的关系;;Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced In?ammation in High-Fat Diet–Induced Obesity and Diabetes in Mice Cani et al.;The conclusions;;炎症与肿瘤;The types and numbers of bacteria associated with biopsy samples were distinctly different for UC and CD patients. ;机制 Mechanisms; ;Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility Uronis et al.;;肠道微生物识别 microbial recognition;TLRs在细菌-炎症-肿瘤过程中起重要的介导作用 ;;The innate immune receptor Nod1 protects the intestine frominflammation-induced tumorigenesis Chen et al.;;Roles for Inflammation and Regulatory T Cells in Colon Cancer ERDMAN et al.;;一些益生菌具有免疫调节及免疫刺激的作用;The formyl peptide receptor (FPR);人类研究;Myeloperoxidase-Positive Cell Infiltration in Colorectal Carcinogenesis as Indicator of Colorectal Cancer Risk Roncucci et al.;结肠腺瘤患者正常黏膜炎症浸润程度增加;;益生菌人类治疗研究 Human studies ;;结肠菌群紊乱与结肠肿瘤发生的关系;