抗生素英文课件精品—— Antibiotic therapy of postoperative sepsis.pptVIP

Antibiotic therapy of postoperative sepsis Markus A. Weigand Department of Anesthesiology and Intensive Care Medicine Justus-Liebig-University Gie?en University Hospital Gie?en and Marburg Campus Gie?en Hit hard and early Preferred antibiotics in severe sepsis Combination therapy Duration of antibiotic therapy Use of antibiotic diversity Conclusion Time is the critical factor ? Rivers et al. 2001 ?Early goal-dircted therapy“ ScVO2≥70% reduces mortality by 15% Kumar et al. 2006 Each hour of delay in antimicrobial administration was associated with a decrease in survival of 5 – 10% 6 h Ku