【精品英文课件】Stature in adolescent twins教学资料讲义教学资料讲义.pptVIP

;;Bimodality: Hallmark of a major gene effect on a quantitative trait.;Bimodality: Hallmark of a major gene effect on a quantitative trait.;CHGA genetic variation: Risk factor for hypertensive ESRD in blacks;;“Intermediate” in time and causality ;Twins: window into heritability (h2) of any phenotype; Total mole count for MZ and DZ twins;;Family studies (twin pairs, pedigrees). Fam hx as a risk factor. In 1st degree relatives: Parents, siblings. Heritability (h2): Fraction of trait variance accounted for by genetic variance. VP = VG + VE h2 = V