(精选)The ORCHID project教学课件.pptVIP

The ORCHID project Dr Ian Gaywood, NUH Dr Ira Pande, NUH Professor John Chelsom, City University London So much information……so little use Clinical care generates enormous amounts of information which is difficult to use when caring for the individual and impossible to use for any secondary purpose The origins of ORCHID Better organised information has the potential to provide an enormously valuable resource but must be achieved without additional onerous burden at the clinical coalface The greatest impediment to extended uses of clinical records, including research, is not lack of data. It is lack of useable data It should be possible to organise data in ways which allow any plausible question to be answered Stratified medicine Treatment decisions in all but the simplest conditions increasingly rely on knowledge of the patient’s disease phenotype in several domains Current methods of gathering and organising data don’t place information in its correct context The relationships among pieces of information are at least as important as the information itself. It is no longer enough to simply ‘name the beast’ What clinicians want …. A way of organising data which: Identifies patient phenotypes to any degree of detail Produces untainted cohorts Is multidisciplinary Can include or exclude individual disease characteristics Can include or exclude treatment details Records and assesses outcomes Can be searched in real time Maps to existing coding systems The ORCHID information model The two central tools of ORCHID are hierarchies and core data sets Together they provide a rich data architecture which can be applied to all data sets across all specialties ORCHID hierarchies cross-map to existing coding systems but overcame many of their limitations ORCHID hierarchies can be rapidly amended to reflect changes in knowledge and understanding without compromising the value of existing data Existing data sets can be embedded in ORCHID hierarchies and will inherit the richness